Human growth hormone (HGH), also known as somatotropin, is a peptide hormone produced by the pituitary gland that plays a key role in growth, cell reproduction and regeneration. HGH levels naturally decline with age, but synthetic versions are used therapeutically for certain conditions.
Effects of HGH on bone:
- HGH directly stimulates the growth of bone cells (osteoblasts). It causes these cells to grow, mature and deposit bone tissue.
- It also has an indirect effect by stimulating the liver and other tissues to produce Insulin-Like Growth Factor-1 (IGF-1). This growth factor also promotes bone formation.
- Through these mechanisms, HGH has been shown in studies to increase bone mineral density, bone mass and bone strength. It leads to an anabolic effect on skeletal tissue.
Conditions where HGH is used:
- Growth hormone deficiency - Low HGH levels can impair growth during childhood. Replacement therapy is used to restore normal development.
- Turner syndrome - This chromosomal disorder can lead to short stature during youth. HGH therapy helps increase adult height.
- Prader-Willi syndrome - Muscle weakness and growth failure are treated with HGH.
- Chronic kidney disease - HGH reverses some signs of renal osteodystrophy and mineral bone disease.
- Idiopathic short stature - The FDA has approved HGH to increase height in children who are significantly shorter than average and do not have an identifiable cause.
Other key facts:
- The effects tend to be most pronounced during youth and puberty when the skeleton is still growing. But benefits on bone density can occur at any age.
- HGH must be administered as an injection under the skin (subcutaneous injection).
- Like any medication, HGH has potential side effects. These may include joint pain, edema, carpal tunnel syndrome, glucose intolerance or diabetes risk at high doses.
- Skeletal overgrowth and joint swelling are concerns if excessive doses are given during development. Doses should be carefully controlled under medical guidance.
Overall, research shows
human growth hormone fulfills an important role in the attainment of peak bone mass during adolescence and the maintenance of bone health later in life. Responsible medical supervision is vital, but HGH therapy -
when properly administered - can help strengthen bones and reduce the risk of debilitating fractures due to osteoporosis or aging.
If you have struggled with growth concerns or bone health issues, the caring medical team at
Elite Hormone Health has extensive experience with HGH replacement regimens. Conveniently located in and led by renowned endocrinologist Dr. * Elite Hormone Health utilizes state-of-the-art diagnostic testing and individually tailored treatment plans to help you achieve your wellness goals. Contact us today to schedule a consultation and learn if HGH therapy is right for you.